In vitro patient-specific study of the Norwood procedure

Authors:

Tianqi Hang

PI/Advisor:

Richard S. Figliola, PhD, PE

Program:

Mechanical Engineering (College of Engineering and Science)

Abstract:

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where there is a rudimentary left ventricle so that systemic perfusion solely depends on the right ventricle ejecting to the systemic circulation. The Norwood procedure represents the first of the three procedures, in the surgical management of children with HLHS. The goal of Norwood procedure is to allow mixing between blood in the systemic circulation with blood in the pulmonary circulation by inserting an shunt between the aorta and the pulmonary arteries. The dimension of the shunt is critical because congenital deformations of each patient are different.Norwood procedure is known for chronic complications and low survival rate due to its complexity. In vitro patient specific study of Norwood procedure is a new tool that can be used in planning and improving Norwood surgical treatment, testing new medical device and the training of physicians. A mock circulatory system is built around a lumped parameter model to the circulation and the 3D aortic teats section with shunt. The system elements are set to patient-specific values, under which flow rate and pressure signal are collected. System function are verified against the analytical model on which it is based by analyzing the data collected.

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